After earning his BSc at Trent University in 2000 and his PhD at York University in 2005, Jeffrey Smith worked as a post-doctoral fellow and a research associate at the Ottawa Institute of Systems Biology at the University of Ottawa. In 2008, he was hired as a faculty member at Carleton University, where he is an Associate Professor in the Department of Chemistry and the Institute of Biochemistry. His research program includes the use of mass spectrometry and microfluidics to develop novel quantitative proteomic and lipidomic strategies, which are then used to monitor the dynamics of proteins and lipids from a systems biology point of view.

Dr. Smith is an expert in mass spectrometry and uses these techniques to understand biomolecular dynamics of living systems including proteins, lipids, and xenobiotics. The Director of the Carleton Mass Spectrometry Centre (CMSC), he maintains a diverse group of collaborations with researchers from numerous Canadian institutions including the University of New Brunswick, the University of Ottawa, the Ottawa Hospital Research Institute, and the Royal Canadian Mounted Police. He has been funded by the Canadian Institutes of Health Research, the Natural Sciences and Engineering Research Council, the Canada Foundation for Innovation, and the Ontario Research Fund.